Between 2007 and 2012, 11 drug distributors shipped 59.9 million oxycodone pills and 140.6 million hydrocodone pills to West Virginia.
The wholesalers’ pain-pill numbers were culled from a U.S. Drug Enforcement Administration database, according to the filing.
In previous filings, the drug wholesalers have said raw pill counts can be misleading. The companies argue that their total distribution numbers, and the percentage of sales of controlled substances compared to all drugs, would put the records in better context.
The release of the pill numbers follows a bid by the drug wholesalers to toss out the lawsuit.
The records are voluminous.
New guidelines from the Centers for Disease Control and Prevention urge doctors to take it easy in prescribing the potentially killer drugs.
CDC says deaths from opioid overdoses have hit an all-time record in the U.S.
"Compassion for patients does not mean the elimination of all pain," Lee wrote in a commentary in JAMA on the guidelines.
"There is, quite simply, no 'getting it right' when it comes to pain. It is both undertreated and overtreated."
Related: Do you read the dosage label? Americans taking too many pain meds.
'For example, cognitive behavioral therapy (CBT) had small positive effects on disability and catastrophic thinking," the CDC team wrote.
"For the vast majority of patients, the risks will outweigh the benefits for chronic pain," Frieden told reporters in a conference call.
But other things work, too, to help chronic pain, they pointed out.
"The best treatment isn't always the one that provides the most immediate relief," Frieden said.
"We are not a regulatory agency so these are guidelines," he said.