Oxycodone Side Effects in Detail

Oxycodone Side Effects in Detail


Hotoprete.bizOxycodone side effects
7/17/2016
03:14 | Hannah Hoggarth
Oxycodone side effects
Oxycodone Side Effects in Detail

Pregnancy Category B No proven risk in humans.

As well as its needed effects, oxycodone may cause unwanted side effects that require medical attention.

Approval History Calendar Drug history at FDA.

1. "Product Information. OxyContin (oxycodone)." Purdue Frederick Company, Norwalk, CT.

In pediatric patients, the most frequently observed adverse reactions included vomiting, nausea, headache, pyrexia, and constipation. The most commonly reported adverse reactions in adults included constipation, nausea, somnolence, dizziness, vomiting, pruritus, headache, dry mouth, asthenia, and sweating.

Very common (10% or more): Headache (14%, pediatrics) Common (1% to 10%): Dizziness (pediatrics) Frequency not reported: Confusion, hypertonia, hypesthesia, nervousness, neuralgia, personality disorder, tremor, migraine.

Common (1% to 10%): Pruritus, hyperhidrosis, rash Frequency not reported: Herpes simplex, rash, sweating, urticaria.

Abdominal pain and gastroesophageal reflux disease were reported in 1% to less than 5% of patients. In pediatric studies with the oral extended release product, gastrointestinal adverse events were reported in 40% of patients 11 to 16 years of age (56 of 140); vomiting, nausea, constipation, and diarrhea were experienced by 21%, 15%, 9%, and 6%, respectively.

" Lancet 1 (1977): 759-60. 10. Gardos G "Dyskinesia after discountinuation of compound analgesic containing oxycodone.

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See below for a comprehensive list of adverse effects. Other side effects include weakness, xerostomia, and diaphoresis. Commonly reported side effects of oxycodone include constipation, nausea, pruritus, drowsiness, and vomiting.

The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. This material does not endorse drugs, diagnose patients, or recommend therapy. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill, knowledge, and judgement of healthcare practitioners in patient care. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof.

Glare PA, Walsh TD "Dose-ranging study of oxycodone for chronic pain in advanced cancer." J Clin Oncol 11 (1993): 973-8. 5.

Very common (10% or more): Nausea (23% to 27%), constipation (23% to 26%), vomiting (12% to 14%) Frequency not reported: Abdominal pain, anorexia, diarrhea, dyspepsia, dysphagia, gingivitis, glossitis.

For Healthcare Professionals Applies to oxycodone: compounding powder, oral capsule, oral concentrate, oral solution, oral tablet, oral tablet extended release.

Frequency not reported: Photosensitivity reaction, amblyopia.

As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:. Some oxycodone side effects may not need any medical attention.

" J Clin Psychopharmacol 8 (1988): 441-2. 8. Fishbain DA, Goldberg M, Rosomoff RS, Rosomoff H "Atypical withdrawal syndrome (organic delusional syndrome) secondary to oxycodone detoxification.

Common (1% to 10%): Dysuria, urinary retention Frequency not reported: Urinary tract infection.

CSA Schedule 2 High potential for abuse.

Frequency not reported: Back pain, neck pain, arthralgia, arthritis, bone pain, myalgia, pathological fracture.

Frequency not reported: QTc prolongation at higher doses, deep thrombophlebitis, heart failure, hemorrhage, hypotension, palpitation, tachycardia, edema, peripheral edema, vasodilation, circulatory collapse.

Applies to oxycodone: oral capsule, oral solution, oral tablet, oral tablet extended release.

Very common (10% or more): Pyrexia (11%, pediatrics) Frequency not reported: Chills and fever, accidental injury.

WADA Class WADA Anti-Doping Classification.

Sunshine A, Olson NZ, Zighelboim I, Decastro A "Ketoprofen, acetaminophen plus oxycodone, and acetaminophen in the relief of postoperative pain." Clin Pharmacol Ther 54 (1993): 546-55. 4.

3. Glare P, Walsh D "Dose-ranging study of oxycodone for advanced cancer pain (meeting abstract)." Proc Annu Meet Am Soc Clin Oncol 10 (1991): a1201.

Frequency not reported: Allergic reaction.

Severe adverse effects such as respiratory depression can be treated with the opioid antagonist naloxone.

Common (1% to 10%): Decreased appetite (pediatrics) Frequency not reported: Gout, hyperglycemia, iron deficiency anemia.

Data sources include Micromedex (updated Mar 30th, 2016), Cerner Multum (updated Apr 1st, 2016), Wolters Kluwer (updated Apr 1st, 2016) and others. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. To view content sources and attributions, please refer to our editorial policy. provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products.

Leow KP, Smith MT, Williams B, Cramond T "Single-dose and steady-state pharmacokinetics and pharmacodynamics of oxycodone in patients with cancer." Clin Pharmacol Ther 52 (1992): 487-95. 6.

Frequency not reported: Increased hepatic enzymes.

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9. Fanoe S, Jensen GB, Sjogren P, Korsgaard MP, Grunnet M "Oxycodone is associated with dose-dependent QTc prolongation in patients and low-affinity inhibiting of hERG activity in vitro." Br J Clin Pharmacol 67 (2008): 172-9.

Leow KP, Smith MT, Watt JA, Williams BE, Cramond T "Comparative oxycodone pharmacokinetics in humans after intravenous, oral, and rectal administration." Ther Drug Monit 14 (1992): 479-84. 2.

Always consult a healthcare professional for medical advice. These can be reported to the FDA here. It is possible that some side effects of oxycodone may not have been reported.

Cerner Multum, Inc. 7. "UK Summary of Product Characteristics." O 0.

Frequency not reported: Apnea, respiratory arrest, bronchitis, cough increased, dyspnea, epistaxis, laryngismus, lung disorder, pharyngitis, rhinitis, sinusitis.

Frequency not reported: Paranoia, psychosis, hallucinations, agitation, anxiety.

Frequency not reported: Flu syndrome, infection, sepsis.

Availability Rx Prescription only.

If any of the following side effects occur while taking oxycodone, check with your doctor immediay:

If any of the following symptoms of overdose occur while taking oxycodone, get emergency help immediay:

Oxycodone side effects