Each capsule contains 4.5, 9, or 18 mg of oxycodone as 5, 10, or 20 mg situation where opioids are contraindicated: respiratory depression.
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Use in non-malignant pain:. OxyNorm capsules should not be used in patients under 18 years.
Before you contact this company : often several companies will market medicines with the same active ingredient. Why? oxycodone hydrochloride.
CONTRAINDICATIONS. Oxycodone and acetaminophen tablets should not be administered to patients with known hypersensitivity to oxycodone.
The respiratory depressant effects of opioids include carbon dioxide retention and secondary elevation of cerebrospinal fluid pressure, and may be markedly exaggerated in the presence of head injury, other intracranial lesions or a preexisting increase in intracranial pressure. Oxycodone produces effects on pupillary response and consciousness which may obscure neurologic signs of worsening in patients with head injuries.
Loop Diuretics: The effects of the loop diuretic may be decreased because acetaminophen may decrease renal prostaglandin excretion and decrease plasma renin activity.
Oxycodone may cause spasm of the Sphincter of Oddi and should be used with caution in patients with biliary tract disease, including acute pancreatitis.
PERCODAN tablets are contraindicated in patients with known hypersensitivity to oxycodone or aspirin, and in any situation where opioids or aspirin are.
Caution should be taken to monitor for decreased bowel motility in postoperative patients receiving opioids. Standard supportive therapy should be implemented. Ileus is a common postoperative complication, especially after intra-abdominal surgery with use of opioid analgesia. Oxycodone and other morphine-like opioids have been shown to decrease bowel motility.
Aspirin is hydrolyzed primarily to salicylic acid in the gut wall and during first-pass metabolism through the liver. High concentrations are found in the liver and kidneys.
Patients must meet the full indications and usage for treatment with OxyContin, and be assessed for the contraindications of OxyContin. In addition, healthcare.
There are no adequate and well-controlled studies in pregnant women. OxyContin should be used during pregnancy only if the potential benefit justifies the risk to the fetus. OxyContin is a Pregnancy Category C drug.
Therefore, in the setting of hepatic impairment, start dosing patients at 1/3 to 1/2 the recommended starting dosage, followed by careful dosage titration. A study of OxyContin in patients with hepatic impairment demonstrated greater plasma concentrations than those seen at equivalent doses in persons with normal hepatic function.
OxyContin is contraindicated in patients with:
However, reduce the recommended starting dosage to 1/3 to 1/2 the usual dosage in debilitated, non–opioid-tolerant patients.
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