OxyNorm Capsules (Immediate-Release) Pharmacokinetic (PK) A Single Dose PK Study of OxyNorm immediate-release capsules 5, 10, and 20mg, dose-proportionality, and evaluate drug accumulation of Oxycodone.
Multiple dose: The subjects will take 3 days OxyNorm capsule 10mg, once every 6 hours, 10mg per dose. On the 5th day, all the subjects complete the study. Inclusion Criteria: Exclusion Criteria:. In the morning of the 4th day, the subjects will take single dose of OxyNorm capsule 10mg.
Example: "Heart attack" AND "Los Angeles".
Single dose: The subjects will be randomized to receive a single dose of OxyNorm immediate-release capsules 5, 10, and 20mg.
Oxycodone Tablets and Immediate-Release Oxycodone Solution. DAVID P. controlled-release (CR) tablet or a 20 mg immediate-release (IR) solution.
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