Oxycodone (OxyContin)

Oxycodone (OxyContin)

04:31 | Joshua Addington
Oxycodone (OxyContin)

OxyContin is a brand of timed-release oxycodone, made by Purdue Pharma, that works for up to 12 hours.

Like all opioid painkillers, oxycodone has come under increased scrutiny by law enforcement officers, healthcare providers, and government officials due to its potential for abuse.

A: Yes, Endocet and Percocet are both brands of oxycodone with acetaminophen. Jeff O'Connell, PharmD.

A: Oxycodone is a narcotic pain reliever similar to morphine. Oxycodone is commonly used to treat moderate to severe pain. Common side effects for oxycodone include nausea, vomiting, constipation, loss of appetite, dizziness, headache, feeling tired, dry mouth, sweating, and itching. The FDA pregnancy category for oxycodone is a category C. This means oxycodone may be harmful to an unborn baby, and could cause addiction or withdrawal symptoms in a newborn. l your doctor if you are pregnant or plan to become pregnant during treatment. Oxycodone can pass into breast milk and may harm a nursing baby. Do not use this medication without ling your doctor if you are breast-feeding a baby. For more information on oxycodone, visit our Web site /drugs/oxycodone. When your doctor prescribes a new medication, be sure to discuss all your prescription and over-the-counter drugs, including dietary supplements, vitamins, botanicals, minerals, and herbals, as well as the foods you eat. Always keep a current list of the drugs and supplements you take and review it with your health care providers and your pharmacist. If possible, use one pharmacy for all your prescription medications and over-the-counter products. This allows your pharmacist to keep a complete record of all your prescription drugs and to advise you about drug interactions and side effects. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Jennifer Carey, PharmD.

Common Conditions.

Small amounts of the drug secreted in breast milk may also cause side effects in breastfeeding babies.

The typical dosages of oxycodone for adults with pain are as follows:

Call your doctor immediay or seek emergency medical help if you experience any of the following severe symptoms:

Oxycodone can also be habit-forming. Take it exactly as your doctor prescribed, not in higher doses or more often.

Abuse of oxycodone or other opiate painkillers can result in severe side effects, including unconsciousness, breathing problems including stopped breathing, and death.

Oxycodone overdose symptoms include:

Oxycodone withdrawal symptoms, such as insomnia, anxiety, pain, and nausea, can be managed with the help of your doctor.

Oxycodone is available by itself or in combination with other substances, including acetaminophen (Tylenol ), aspirin (Bayer, Bufferin) and ibuprofen (Advil, Motrin, Mydol).

Immediate release form: 10 mg to 30 mg, every four hours.

A: Oxycodone is in a class of drugs called opioid analgesics. Oxycodone is used to treat moderate to severe pain -- when the use of an opioid analgesic is appropriate. Oxycodone works by altering the way in which the brain and nervous system respond to pain. In a clinical study supporting the development of oxycodone, too few people with decreased liver function were included in the study to conclude if people with decreased liver function differ from people with normal liver function in regards to how their body handles oxycodone. However, according to oxycodone prescribing information, oxycodone is extensively metabolized (cleared from the body) by the liver. The clearance of oxycodone from the body may decrease in people with liver failure. Thus, according to oxycodone prescribing information, the starting dose of oxycodone in people with liver impairment should be conservative; that is, on the lower side. And, dose adjustment should be evaluated on a case by case basis -- depending on various patient-specific factors. Cirrhosis is a consequence of chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue and regenerative nodules (lumps that occur as a result of a process in which damaged tissue is regenerated), leading to loss of liver function. Cirrhosis is most commonly caused by alcoholism, hepatitis B and C, and fatty liver disease, but has many other possible causes. Cirrhosis is the twelfth leading cause of death by disease and affects men slightly more often than women. Derek Dore, PharmD.

There are serious health risks associated with using oxycodone, including severe or life-threatening breathing problems, particularly in the first 72 hours of treatment and any time the dose is increased.

l your doctor if you are pregnant, might become pregnant, or are breastfeeding before taking oxycodone.

Taking other medications with oxycodone may increase your risk of breathing problems. l your doctor about all medicines, including supplements, that you are taking.

Oxycodone may also make you drowsy. Do not drive a car, operate machinery, or take part in other potentially risky activities that require clear judgment or quick reactions until you know how the drug affects you.

l your doctor if you have or have ever had slowed breathing or asthma; lung disease such as chronic obstructive pulmonary disease (COPD ); a head injury or any condition that increases the pressure in your brain; or kyphoscoliosis (curving of the spine that may cause breathing problems).

The drug is in a class of medications called opioid analgesics; they work by changing the way your brain and nervous system respond to pain.

A: This answer depends on how much you take and for how long you have been taking the medication oxycodone. One tablet can last in your system up to 3 days, so if you are taking it on a daily basis, you are probably looking at about one month to become compley free of the medication. Every person metabolizes medication at a different rate, so it is hard to say exactly when the medication will be out of your system.

More than 100,000 U.S. deaths have been caused by prescription opioids such as oxycodone since drug-prescribing policies became more liberal in the late 1990s, according to a 2014 statement from the American Academy of Neurology (AAN).

l your doctor if you or a family member has a history of alcohol abuse, drug addiction, or mental illness.

However, if it's almost time for the next dose, skip your missed dose and continue on your regular dosing schedule.

Drinking alcohol while taking oxycodone may increase your risk of serious, life-threatening side effects.

A: Sweating can be a common side effect of Oxycontin (oxycodone). If you find the side effect bothersome, contact your health care provider. You may also find helpful information at /drugs/oxycontin Sarah, PharmD.

The combined formulations of oxycodone and acetaminophen have brand names such as Norco, Vicodin, or Lortab. You should read about all the ingredients if you are a taking a combination product that contains oxycodone.

A: MS Contin (morphine sulfate ER) works by stimulating opiate receptors in the central nervous system (CNS). MS Contin are formulated as long-acting products that are taken every 12 hours. MS Contin is indicated for long-term pain control and not for as PRN use. Swallow the MS Contin tablet whole and do not crush, chew or break the controlled-release tablets. Breaking the tablet could cause too much of the drug to be absorbed into the body at one time. Also, do not suddenly stop taking the MS Contin unless directed by the doctor. Abruptly stopping could cause withdrawal symptoms such as nausea, vomiting, cramps, fever, faintness, anorexia (loss of appetite). MS Contin can be taken with or without food about 12 hours apart. Common side effects of MS Contin include constipation, nausea, stomach pain, dizziness, headache, and drowsiness. MS Contin is distributed to the skeletal muscle, kidneys, liver, intestines, lungs, spleen, brain, and also crosses membrane into the breast milk. Almost all of the drug is converted into a major metabolite call morphine-3-glucuronide. The elimination half-life of MS Contin is 2-4 hours. Most MS Contin should be out of the body a day or two after the last dose. Oxy IR (oxycodone) is indicated for break-through pain. Common side effects of Oxy IR include dry mouth, dizziness, constipation, and headache. Oxy IR is metabolized in the liver to the major metabolite noroxycodone and other metabolites xylophone and glucuronides. The elimination of the half-life is 0.4 hours. Many factors may contribute to the elimination of drug. Factors may include the person's age, weight, dose, how long the drug has been taken and other factors. Consult with your healthcare provider if you are concerned about the MS Contin or Oxy IR showing on a drug screen. Most prescription medications should not be a problem with drug screens as long as the drug is documented and taken under the supervision of a healthcare provider. Kimberly Hotz, PharmD.

Oxycodone is a narcotic medication used to relieve moderate to severe pain.

Don’t stop taking oxycodone without first talking with your doctor because of the risk of withdrawal symptoms.

Your baby could experience life-threatening withdrawal symptoms if you use oxycodone while pregnant.

If you are taking the concentrated form of oxycodone, your doctor may advise that you mix it with a small amount of juice or semi-solid food such as pudding or applesauce.

People sometimes abuse oxycodone for the narcotic "high" it can provide.

Immediate release form: 5 milligrams (mg) to 15 mg, every four to six hours.

Don't “double up” to make up for a missed dose, and don't take more than one dose of the extended-release tablets in a 12-hour period.

The medication comes in a liquid, concentrated liquid, tablet, capsule, and extended-release tablet. The extended-release tablets are used in patients who need round-the-clock pain relief.

Oxycodone may cause several side effects. You should l your doctor if any of the following symptoms are severe or do not go away:

Controlled release form: 20 mg to 640 mg, per day in patients with cancer pain. The average total daily dose is about 105 mg per day.

Controlled release form: 10 mg every 12 hours.

You should be especially careful to keep oxycodone out of the reach of children and teenagers. This medication can cause harm or death, particularly to children and teenagers.

A: Switching from oxycodone to Vicodin (hydrocodone and acetaminophen) may be safe depending on the level of pain being treated, and the level of tolerance or physical dependence on the oxycodone. People who are taking large doses of oxycodone for extended periods may experience withdrawal symptoms if switched to hydrocodone at a much lower dose. Consult your physician about slowly tapering the dose of pain medication. Each person is unique in their response to chronic pain and pain medications. The best way to treat pain is with a multifaceted approach; physical therapy, massage, exercise, nerve blocks, and heat or cold therapy are often helpful adjuncts to prescription pain medications. Consult your physician and check out the Everyday Health Pain Management Center for more information. Burton Dunaway, PharmD.

l your doctor about all prescription, non-prescription, illegal, recreational, herbal, nutritional, or dietary drugs you are taking.

Oxycodone was approved by the Food and Drug Administration (FDA) in 1976.

A: Oxycontin (oxycodone extended-release) is a prescription medication approved to treat moderate to severe pain. It is a strong narcotic painkiller that should not be used to treat mild or short-term pain. Oxycontin is meant to be used around the clock at scheduled times twice a day. It is not approved for "as needed" use (unscheduled use only when needed). Taking Oxycontin three times daily (instead of the officially recommended twice daily dosage) is a common off-label use of the drug. It is not appropriate for treating pain after a surgery, unless your pain is expected to be moderate to severe and long-lasting. Some side effects with Oxycontin are potentially serious and should be reported immediay to your health care provider. These include, but are not limited to: the urge to take more Oxycontin than prescribed or for a non-medical purpose, falling or unsteadiness, unusual changes in mood or behavior, severe constipation, confusion, slow heart rate (bradycardia), difficulty passing urine, low blood pressure, slow or irregular breathing, severe drowsiness, and seizures. Oxycontin is a very effective pain medication that can be quite safe when used properly. However, it also has significant abuse potential. health care providers and patients alike must take measures to make sure the medication is used to its fullest potential while minimizing the risks for addiction to Oxycontin. As with other narcotics, the body becomes physically dependent upon Oxycontin. This is a predictable, physical response to long-term use of the narcotic. The body becomes accustomed to physical changes that Oxycontin causes, and stopping the drug will lead to withdrawal symptoms. It is important to understand that physical dependence on Oxycontin is not necessarily a sign of addiction, at least in the sense that most people use the term. Even people taking Oxycontin responsibly for a legitimate medical purpose will become physically dependent on the drug. Friends and family can keep an eye out for signs of addiction, such as: Secluded behavior, often needing to spend large amounts of time alone Stealing, lying, or other dishonest behavior An unexplainable lack of money Changes in social circles, such as abandoning good friends and replacing them with new ones Unexplained changes in mood or behaviors. If there are concerns in regard to this medication, the physician should be consulted as they know the patient and his condition. Here is some information on Oxycontin: /drugs/Oxycontin. Lori Mendoza, PharmD Poulin, PharmD.

If you forget a dose of oxycodone, take the missed dose as soon as you remember.

About 50 percent of people who take opioid pain medication for at least three months are still using opioids five years later, the AAN states, and the long-term use of opioid painkillers remains controversial.

l your doctor if you have or have ever had a blockage in your stomach or intestine; low blood pressure; seizures; paralytic ileus (where digested food does not move through the intestines); Addison’s disease (where the adrenal glands do not produce enough hormone); an enlarged prostate; or heart, liver, kidney, pancreas, thyroid, or gallbladder disease.

If you're taking OxyContin, the extended-release form of oxycodone, l your doctor if you have ever had diverticulitis, colon cancer, or esophageal cancer.

A: Oxycodone is a medication that is used to treat moderate to severe pain. It is classified in the group of medications known as narcotic pain relievers that is similar to morphine. Oxycodone comes in several different forms, reflecting the many different ways the drug can be used. Oxycodone 30 mg tablets would be the short-acting product, or immediate release form, that are most useful for treating temporary pain or breakthrough pain (occasional pain that occurs despite treatment with longer-acting pain medications). Oxycontin (oxycodone extended-release) is a long-acting tablet that is usually used when continuous, around-the-clock use of potent opioid medications is necessary for an extended period of time (for more than a few days). Lori Poulin, PharmD.

A: Depending on the dose of prednisone you are taking, this may be slowing down your weight loss goals. Prednisone has a tendency to cause fluid retention which can cause this to happen. Discuss this situation with your health care provider. Do not stop taking any of your medications without talking to your provider first.

The following medications are some of the many that may interact with oxycodone:

A: Without knowing more information such as your medical history, how long have you been using oxycodone, the type of pain, and your other current medications, it would be too dangerous to council you on how to wean yourself off this very potent narcotic painkiller. This really is a question your physician should answer for you. For general information on oxycodone, please look at our Web site; /drugs/oxycodone For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. William Gault, RPh, PharmD.

A: Your question concerns the length of time oxycodone-acetaminophen ( /drugs/acetaminophen-oxycodone ) stays in the system. The half-life of a drug is the amount of time it takes for one-half of the dose to be eliminated from the body. The half-life of oxycodone-acetaminophen is between three and four and a half hours. Dosing is based on everyone's uniquely individual response to pain medications, and the type of pain and its expected duration. Also, if the pain is chronic or of a very long duration, then a tolerance will be built up over time and the dose will need to be adjusted. Every four hours is a commonly prescribed frequency for oxycodone-acetaminophen. It is essential to frequently check with one.

A: Oxycodone/APAP (Percocet) is a combination opioid and nonopioid analgesic used to treat moderate to severe pain. Oxycodone/Apap 7.5mg/325mg contains two medications, oxycodone at a dose of 7.5mg and acetaminophen (Tylenol) at a dose of 325mg. Oxycodone (OxyIR) is an opioid analgesic used to treat moderate to severe pain. Oxycodone 5mg contains one medication; oxycodone at a dose of 5mg. Oxycodone/APAP 7.5mg/325mg has a higher oxycodone dose than oxycodone 5mg and it contains an additional medication, acetaminophen. The most common side effects with oxycodone/APAP and oxycodone are drowsiness, dizziness, itching, nausea, constipation, and vomiting. Laura Cable, Pharm.D., BCPS.

To avoid withdrawal symptoms, medical experts advise gradually reducing your dose of oxycodone, instead of suddenly stopping your use of the drug.

If you take oxycodone extended-release tablets, swallow them whole. Do not chew, break, divide, crush, or dissolve them.

A: Oxycodone is a narcotic pain reliever, similar to morphine, that is used to treat moderate to severe pain. It is in many pain relievers (Percocet, Endocet, Percodan) as well as by itself as an immediate release or extended release form. Oxycodone is an immediate release form of the medication and is used to treat pain in the short-term. It works by binding to opioid receptors in the body and produces pain relief, cough suppression, decreased breathing, and slowing of digestion. Oxycontin (oxycodone ER) is the extended-release formulation of oxycodone and works by releasing the medication slowly over 12 hours. It is a strong narcotic pain reliever that should not be used to treat mild or short-term pain. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Lori Poulin, PharmD.

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A: Oxycontin (oxycodone) and Percocet (oxycodone/acetaminophen) are both pain relievers, but there is a difference. Oxycodone comes in a long-acting form that should only be take twice a day and should be taken whole, not crushed or chewed. Percocet contains the short-acting form of oxycodone and is take up to three or four times daily. Your doctor should help you decide which is better for you, depending on your medical condition. If you can't take acetaminophen, then you shouldn't use Percocet. For more information on each medication, go to /drugs/percocet-5-325 and /drugs/oxycontin. Gerald Levy, RPh.

If you suspect an overdose of oxycodone, contact a poison control center at (800) or emergency room immediay.