Common side effects may include:
Serious, life-threatening, or fatal respiratory depression may occur with use of OXYCONTIN. Monitor for respiratory depression, especially during initiation of OXYCONTIN or following a dose increase. Instruct patients to swallow OXYCONTIN tablets whole; crushing, chewing, or dissolving OXYCONTIN tablets can cause rapid release and absorption of a potentially fatal dose of oxycodone.
Report Problems to the Food and Drug Administration.
OXYCONTIN exposes patients and other users to the risks of opioid addiction, abuse and misuse, which can lead to overdose and death. Assess each patient's risk prior to prescribing OXYCONTIN and monitor all patients regularly for the development of these behaviors or conditions.
If opioid use is required for a prolonged period in a pregnant woman, advise the patient of the risk of neonatal opioid withdrawal syndrome and ensure that appropriate treatment will be available. Prolonged use of OXYCONTIN during pregnancy can result in neonatal opioid withdrawal syndrome, which may be life-threatening if not recognized and treated, and requires management according to protocols developed by neonatology experts.
Visit the FDA MedWatch website or call 1-800-FDA-1088. You are encouraged to report negative side effects of prescription drugs to the FDA.
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Before taking oxycodone, l your doctor or pharmacist if you are allergic to it; or to other narcotic pain relievers (such as oxymorphone); or if you have any other allergies. Talk to your pharmacist for more details. This product may contain inactive ingredients, which can cause allergic reactions or other problems.
The 60 mg tablets also contain polysorbate 80, red iron oxide and black iron oxide.
"The US Food and Drug Administration (FDA) has approved diclofenac sodium injection ( Dyloject, Hospira Inc), a proprietary nonsteroidal anti-inflammatory drug (NSAID) for the treatment of mild to moderate pain, and for the management of mod".
Before using this medication, l your doctor or pharmacist your medical history, especially of: brain disorders (such as head injury, tumor, seizures), breathing problems (such as asthma, sleep apnea, chronic obstructive pulmonary disease-COPD), kidney disease, liver disease, mental/mood disorders (such as confusion, depression), personal or family history of regular use/abuse of drugs/alcohol, stomach/intestinal problems (such as blockage, constipation, diarrhea.
The 15 mg tablets also contain black iron oxide, yellow iron oxide, and red iron oxide.
Accidental ingestion of even one dose of OXYCONTIN, especially by children, can result in a fatal overdose of oxycodone.
The concomitant use of OXYCONTIN with all cytochrome P450 3A4 inhibitors may result in an increase in oxycodone plasma concentrations, which could increase or prolong adverse drug effects and may cause potentially fatal respiratory depression. Monitor patients receiving OXYCONTIN and any CYP3A4 inhibitor or inducer [see WARNINGS AND PRECAUTIONS and CLINICAL PHARMACOLOGY ]. In addition, discontinuation of a concomitantly used cytochrome P450 3A4 inducer may result in an increase in oxycodone plasma concentration.
Oxycodone hydrochloride dissolves in water (1 g in 6 to 7 mL). It is slightly soluble in alcohol (octanol water partition coefficient 0.7). Oxycodone is a white, odorless crystalline powder derived from the opium alkaloid, thebaine.
Read All Potential Precautions of Oxycontin »
The chemical name is 4, 5α-epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one hydrochloride.
The 80 mg tablets also contain hydroxypropyl cellulose, yellow iron oxide and FD&C Blue #2/Indigo Carmine Aluminum Lake.
OXYCONTIN (oxycodone hydrochloride) Extended-release Tablets WARNING.
ADDICTION, ABUSE AND MISUSE; LIFE-THREATENING RESPIRATORY DEPRESSION; ACCIDENTAL INGESTION; NEONATAL OPIOID WITHDRAWAL SYNDROME; and CYTOCHROME P450 3A4 INTERACTION.
The 20 mg tablets also contain polysorbate 80 and red iron oxide.
C 18 H 21 NO 4 •HCl MW 351.83.
FDA Okays Diclofenac Injection (Dyloject) for Pain »
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Here is a collection of user reviews for the medication Oxycontin sorted by most helpful.
The 10 mg tablets also contain hydroxypropyl cellulose.
Read the FDA Okays Diclofenac Injection (Dyloject) for Pain article »
Read All Potential Side Effects and See Pictures of Oxycontin »
Last reviewed on RxList: 8/28/2015 This monograph has been modified to include the generic and brand name in many instances.
The 10 mg, 15 mg, 20 mg, 30 mg, 40 mg, 60 mg and 80 mg tablets contain the following inactive ingredients: butylated hydroxytoluene (BHT), hypromellose, polyethylene glycol 400, polyethylene oxide, magnesium stearate, titanium dioxide.
Stop using oxycodone and call your doctor at once if you have:
The 30 mg tablets also contain polysorbate 80, red iron oxide, yellow iron oxide, and black iron oxide.
The 40 mg tablets also contain polysorbate 80 and yellow iron oxide.
The structural formula for oxycodone hydrochloride is as follows:. The tablet strengths describe the amount of oxycodone per tablet as the hydrochloride salt. OXYCONTIN (oxycodone hydrochloride) extended-release tablets is an opioid analgesic supplied in 10 mg, 15 mg, 20 mg, 30 mg, 40 mg, 60 mg, and 80 mg tablets for oral administration.Oxy drug