Hydrocodone may be habit-forming. Patients should take the drug only for as long as it is prescribed, in the amounts prescribed, and no more frequently than prescribed.
Teratogenic Effects: Pregnancy Category C: There are no adequate and well-controlled studies in pregnant women. Hydrocodone bitartrate and acetaminophen tablets should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Hydrocodone bitartrate and acetaminophen is supplied in tablet form for oral administration.Hydrocodone bitartrate is an opioid analgesic and antitussive and occurs as fine, white crystals or as a crystalline powder.
Hydrocodone Bitartrate and Acetaminophen Tablets USP for oral administration are available in a variety of strengths as described in the following table.
Respiratory Depression: Hydrocodone bitartrate may produce dose-related respiratory depression by acting directly on the brain stem respiratory center (see OVERDOSAGE ).
Hydrocodone also affects the center that controls respiratory rhythm, and may produce irregular and periodic breathing. Respiratory Depression: At high doses or in sensitive patients, hydrocodone may produce dose-related respiratory depression by acting directly on the brain stem respiratory center.
Physical dependence, the condition in which continued administration of the drug is required to prevent the appearance of a withdrawal syndrome, assumes clinically significant proportions only after several weeks of continued narcotic use, although some mild degree of physical dependence may develop after a few days of narcotic therapy.
ZOHYDRO ER (hydrocodone bitartrate) is indicated for the management of pain severe enough to require daily, around-the-clock, long-term opioid treatment.
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Table 1: Conversion Factors to ZOHYDRO ER (Not Equianalgesic Doses) Prior Oral Opioid Oral Dose (mg) Approximate Oral Conversion Factor Hydrocodone 10 1 Oxycodone 10 1 Methadone 10 1 Oxymorphone 5 2 Hydromorphone 3.75 2.67 Morphine 15 0.67 Codeine 100 0.10 The conversion ratios in this table are only to be used for the conversion from current opioid therapy to ZOHYDRO ER.
ZOHYDRO ER should be prescribed only by healthcare professionals who are knowledgeable in the use of potent opioids for the management of chronic pain.
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Use of higher starting doses in patients who are not opioid tolerant may cause fatal respiratory depression.
Strength Capsule Color(s) Capsule Text NDC Number 10 mg White opaque “Z310 10 mg” in black ink 15 mg Light green and white opaque “Z315 15 mg” in black ink 20 mg Light green opaque “Z320 20 mg” in black ink 30 mg Dark blue and white opaque “Z330 30 mg” in black ink 40 mg Dark brown and white opaque “Z340 40 mg” in black ink 50 mg Dark brown opaque “Z350 50 mg” in black ink.
Advise patients to dispose of any unused capsules from a prescription as soon as they are no longer needed in accordance with local State guidelines and/or regulations.
ZOHYDRO ER extended-release capsules are supplied in 60-count bottles with a child-resistant closure as follows:
"Repeated subcutaneous injections of botulinum toxin A ( Botox, Allergan) provides analgesic relief to patients with neuropathic pain, a new randomized controlled trial has shown.
ZOHYDRO ER may be targeted for theft and diversion.
4 Answers - Posted in: norco, acetaminophen, hydrocodone - Answer: Hi Jill, As far as my experience goes, the strongest I know is 10/500.
Hi Jill, As far as my experience goes, the strongest I know is 10/500. 10mgs of (opioid) narcotic to 500mgs of acetominophen.
I take Acetaminophen and hydrocodone bitartrate 500 mg / 2.5 mg.? I have reduced my dose by half so far.
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